(A–C) Cytokine production after in vitro restimulation of LN CD4+ T cells from (A) BALB/c and Myd88−/− BALB/c (B) C57Bl/6, Myd88−/− C57Bl/6, Tlr2−/−;Tlr4−/−, Tlr9−/−, Myd88−/−;Trif−/−, Il1r1−/−, and Il18r1−/−, and (C) C57Bl/6 and Il1rl1−/− (ST2-deficient) mice 5 days after immunization with OVA and bvPLA2. (D) Cytokine production after in vitro restimulation of LN CD4+ T cells from C57Bl/6 and Il1rl1−/− mice 5 days after immunization with OVA with or without LPC. (E) Cytokine production after in vitro restimulation of LN CD4+ T cells from C57Bl/6 and MyD88fl/fl;Cd4-Cre mice 5 days after immunization with OVA and bvPLA2. All error bars show s.e.m. N.S. P>.05; *P<0.05; ***P<0.001. Data are representative of at least three experiments.