Table 2.
Regions with significantly increased functional connectivity with seeds in the basal ganglia-thalamocortical network (putamen, SMA)
| Seed | Region with peak functional connectivity (approximate Brodmann area) (left/right) | Volume (mm3) | max t | x | y | z |
|---|---|---|---|---|---|---|
| L Putamen | Controls > Stuttering | |||||
| Precuneus (L)/parahippocampal gyrus (18/30) (L) | 3162 | 4.6193 | −18 | −54 | 1 | |
| SMA (6)(L) | 2118 | 4.1122 | −4 | −9 | 58 | |
| Posterior cingulate (31/18)(L) | 1695 | 4.5165 | −1 | −70 | 13 | |
| Precuneus (R)/parahippocampal gyrus (17) (R) | 879 | 4.1147 | 16 | −43 | 2 | |
| STG (R) | 671 | 4.7606 | 47 | −40 | 5 | |
| SMA/Cingulate gyrus (6) (L) | 592 | 4.9942 | −8 | −7 | 47 | |
| Insula (13)/OP3/rolandic operculum (L) | 525 | 4.0483 | −37 | −14 | 13 | |
| Stuttering > Controls | ||||||
| SFG (8) (R) | 825 | −4.202 | 40 | 29 | 57 | |
| SFG (R) | 512 | −4.0731 | 35 | 56 | 10 | |
| L SMA | Controls > Stuttering | |||||
| Putamen/lentiform nucleus (L) | 1025 | 4.442 | −23 | 0 | −14 | |
| Cerebellum (Culmen) (VI) (L) | 593 | 3.8968 | −29 | −52 | −23 | |
| pSTG (R) | 426 | 4.419 | 43 | −43 | 15 | |
| Stuttering > Controls | ||||||
| Cerebellum (Crus 1) (L) | 1665 | −4.6237 | −42 | −69 | −34 | |
| Area 4a (paracentral lobule) (R) | 1417 | −3.9516 | 9 | −32 | 66 |
Coordinates are reported in MNI space.
L = left; R = right; STG = superior temporal gyrus; pSTG = posterior superior temporal gyrus; OP3 = Operculum 3; SFG = superior frontal gyrus.