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. 1986 Oct;83(19):7226–7230. doi: 10.1073/pnas.83.19.7226

Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene.

M W Hentze, S Keim, P Papadopoulos, S O'Brien, W Modi, J Drysdale, W J Leonard, J B Harford, R D Klausner
PMCID: PMC386688  PMID: 3020541

Abstract

A genomic phage clone containing a full-length copy of a functional human gene for ferritin heavy chain has been isolated. The gene consists of four exons spanning approximately 3 kilobases and has been localized to chromosome 11. The functionality of the gene was demonstrated by the fact that both transient transfectants and stable transformants of murine fibroblasts actively transcribe human ferritin heavy-chain mRNA.

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