Table 2.
Variable | No. of Patients Who Died | Total No. of Patients | Hazard Ratio (95% CI) | P |
---|---|---|---|---|
HOXB7 expression | ||||
Low | 67 | 90 | 1.00 | .01 |
High | 48 | 55 | 1.63 (1.12–2.36) | |
Age, y | ||||
≤60 | 40 | 49 | 1.00 | .89 |
>60 | 75 | 96 | 1.03 (0.70–1.51) | |
Sex | ||||
Female | 60 | 70 | 1.00 | .11 |
Male | 55 | 75 | 0.74 (0.52–1.07) | |
Greatest tumor dimension | ||||
<3 cm | 65 | 87 | 1.00 | .14 |
≥3 cm | 50 | 58 | 1.33 (0.92–1.92) | |
Histologic grade | ||||
Well + moderate | 60 | 83 | 1.00 | .001 |
Poor | 55 | 62 | 1.88 (1.30–2.74) | |
pT-stage | ||||
pT1 | 23 | 26 | 1.00 | .52 |
pT2 + pT3 | 92 | 119 | 0.86 (0.55–1.36) | |
N-stage | ||||
N0 | 50 | 69 | 1.00 | .002 |
N1 | 65 | 76 | 1.80 (1.24–2.60) | |
AJCC stage | ||||
Stage I | 28 | 40 | 1.00 | .02 |
Stage II | 87 | 105 | 1.67 (1.09–2.55) | |
Margin status | ||||
Negative (R0) | 102 | 126 | 1.00 | .53 |
Positive (R1) | 13 | 18 | 1.21 (0.68–2.15) |
Abbreviations: AJCC, American Joint Commission on Cancer; CI, confidence interval.