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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Medchemcomm. 2013 Oct 15;4(12):10.1039/C3MD00238A. doi: 10.1039/C3MD00238A

Scheme 2.

Scheme 2

Synthesis of anziaic acid analogues 11a-d and 14: Reagents and conditions: (a) 3 (for 13), (CF3CO)2O, toluene, 57–85%; (b) Pd/C, H2, ethyl acetate, 80–100%; (c) SOCl2/acetone/DMAP, 1,2-dimethoxyethane, 0 °C to rt, 39%.