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. 1986 Nov;83(21):8415–8419. doi: 10.1073/pnas.83.21.8415

A Drosophila mutation that eliminates a calcium-dependent potassium current.

T Elkins, B Ganetzky, C F Wu
PMCID: PMC386939  PMID: 2430288

Abstract

A mutation of Drosophila, slowpoke (slo), specifically abolishes a Ca2+-dependent K+ current, IC, from dorsal longitudinal flight muscles of adult flies. Other K+ currents remain normal, providing evidence that IC is mediated by a molecularly distinguishable set of channels. The pharmacological properties of IC are similar to those of Ca2+-dependent currents in some vertebrate cells. The muscle action potential was significantly lengthened in slo flies, indicating that IC plays the major role in its repolarization.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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