Abstract
Human IgG specific for beta-endorphin was identified by enzyme-linked immunoabsorbent assay and isolated by affinity chromatography. From a sample of 27 subjects, three individuals with major depression demonstrated plasma IgG highly reactive with human beta-endorphin, while four other subjects (two with depression and two randomly selected blood donors) had intermediate reactivity. The recognition site for beta-endorphin was retained by F(ab')2 fragments.
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Selected References
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- Hawkins D. R., Mendels J. Sleep disturbance in depressive syndromes. Am J Psychiatry. 1966 Dec;123(6):682–690. doi: 10.1176/ajp.123.6.682. [DOI] [PubMed] [Google Scholar]
- Kripke D. F., Mullaney D. J., Atkinson M., Wolf S. Circadian rhythm disorders in manic-depressives. Biol Psychiatry. 1978 Jun;13(3):335–351. [PubMed] [Google Scholar]
- Mains R. E., Eipper B. A., Ling N. Common precursor to corticotropins and endorphins. Proc Natl Acad Sci U S A. 1977 Jul;74(7):3014–3018. doi: 10.1073/pnas.74.7.3014. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mathews P. M., Froelich C. J., Sibbitt W. L., Jr, Bankhurst A. D. Enhancement of natural cytotoxicity by beta-endorphin. J Immunol. 1983 Apr;130(4):1658–1662. [PubMed] [Google Scholar]
- Nakanishi S., Inoue A., Kita T., Nakamura M., Chang A. C., Cohen S. N., Numa S. Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature. 1979 Mar 29;278(5703):423–427. doi: 10.1038/278423a0. [DOI] [PubMed] [Google Scholar]
- Riley V. Psychoneuroendocrine influences on immunocompetence and neoplasia. Science. 1981 Jun 5;212(4499):1100–1109. doi: 10.1126/science.7233204. [DOI] [PubMed] [Google Scholar]
- Solomon G. F., Levine S., Kraft J. K. Early experience and immunity. Nature. 1968 Nov 23;220(5169):821–822. doi: 10.1038/220821a0. [DOI] [PubMed] [Google Scholar]
- Stein M., Schiavi R. C., Camerino M. Influence of brain and behavior on the immune system. Science. 1976 Feb 6;191(4226):435–440. doi: 10.1126/science.1108202. [DOI] [PubMed] [Google Scholar]
- Todd R. D., Ciaranello R. D. Demonstration of inter- and intraspecies differences in serotonin binding sites by antibodies from an autistic child. Proc Natl Acad Sci U S A. 1985 Jan;82(2):612–616. doi: 10.1073/pnas.82.2.612. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ziegler M. G., Thomas J. A., Jacobowitz D. M. Retrograde axonal transport of antibody to dopamine-beta-hydroxylase. Brain Res. 1976 Mar 12;104(2):390–395. doi: 10.1016/0006-8993(76)90638-7. [DOI] [PubMed] [Google Scholar]