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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Pharmacogenomics. 2013 Sep;14(12):10.2217/pgs.13.141. doi: 10.2217/pgs.13.141

Figure 5. Allele-dependent regulation of endogenous SLC6A3 activity by drugs in rs6347-carrying BE(2)-M17, based on BStop-PCR analysis of mRNA levels.

Figure 5

(A) Characteristic data of BStop-PCR analysis. Lane 1: PCR production without BbvcI-digestion; lane 2: rs6347 homozygote A/A (from SK-N-AS) digested completely by BbvcI; lanes 3, 7 and 10: solvents (lighter color) for drugs in following lanes (lanes 4, 5, 6, 8, 9 and 11: drug treatments; darker color). (B) Quantification of regulation data in (A). One-way ANOVA Tukey: *p < 0.05; **p < 0.01, compared with solvent control (n = 3).