Volume 430 (2010), pp. 461–476
The second sentence of this article's abstract contains an error: the word ‘used’ should be ‘based’. The corrected sentence appears here.
We describe the synthesis and properties of a novel series of non-covalent di-peptide inhibitors of the proteasome based on a capped tri-peptide that was first identified by high-throughput screening of a library of approx. 350000 compounds for inhibitors of the ubiquitin–proteasome system in cells.