Table 3.
Multivariate analysis of MYC immunohistochemistry scores as a predictor of progression free survival and overall survival.*
| Parameter | Hazard Ratio
|
p-value
|
||
|---|---|---|---|---|
| PFS | OS | PFS | OS | |
| MYC score | 2.35 | 1.90 | 0.0009 | 0.034 |
| MIPI score | NS | 3.40 | NS | 0.0009 |
*
log(MYC score) was evaluated controlling for age, LDH, WBC count, MIPI score, ECOG performance status, blastic histology, and Ki-67 proliferation index. Predictors shown are valid in the final parsimonious model derived from backward selection. NS = not statistically significant