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Duplication rate is reduced in strains defective in Holliday structure resolution. The duplication rate is defined as the frequency of duplications attained after 33 generations of growth. Bars in red indicate strains that showed a significant reduction in duplication rate. The bar at the far right indicates the rate in a strain lacking both rrnE and rrnH, both of which lie on the clockwise side of the assayed purHD operon.
