Abstract
The application of magnetic circular dichroism as an optical probe for simultaneous identification and determination of at least two microsomal cytochromes is demonstrated. The assignments of the bands in the spectra of microsomal suspensions are made from the spectra of soluble preparations of cytochrome P-450 obtained from Pseudomonas putida and of cytochrome b5 obtained from rat livers.
Keywords: hemoproteins, hepatic microsomes, drug metabolism, cytochrome P-450, magnetic circular dichroism
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