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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1974 Feb;71(2):413–416. doi: 10.1073/pnas.71.2.413

Transfer RNA Biosynthesis: The Nucleotide Sequence of a Precursor to Serine and Proline Transfer RNAs

B G Barrell *, J G Seidman †, Christine Guthrie ‡, William H McClain †,§
PMCID: PMC388016  PMID: 4521813

Abstract

The nucleotide sequence of a transfer RNA precursor molecule coded by bacteriophage T4 has been determined. The molecule is a single polynucleotide chain which contains two transfer RNA species that are destined to recognize serine and proline. The 3′ -CCAOH termini of both mature transfer RNA species are absent in the precursor molecule; these termini must therefore be added enzymatically at a subsequent stage of maturation. Nucleotide residues unique to the precursor are located at both ends of the molecule and between the two transfer RNA sequences.

Keywords: Bacteriophage T4

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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