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. 1974 Feb;71(2):583–585. doi: 10.1073/pnas.71.2.583

Mitochondrial Membrane Potential: Evidence from Studies with a Fluorescent Probe

Henry Tedeschi 1
PMCID: PMC388052  PMID: 4521825

Abstract

The fluorescence of the probe 3,3′-dihexyl-2,2′-oxacarbocyanine (CC6) has been found to indicate potential across cell membranes. Results obtained in the present study using CC6 and Drosophila mitochondria are in agreement with membrane potentials previously measured by Tupper and Tedeschi using microelectrodes. The results of both studies with Drosophila suggest that the potential across the mitochondrial membrane does not play a significant role in oxidative phosphorylation.

Keywords: 3,3′-dihexyl-2,2′-oxacarbocyanine; Drosophila virilis; oxidative phosphorylation

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Selected References

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