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. 1974 Mar;71(3):680–684. doi: 10.1073/pnas.71.3.680

In Vivo Repair of the Single-Strand Interruptions Contained in Bacteriophage T5 DNA

Ronald C Herman 1, Richard W Moyer 1
PMCID: PMC388076  PMID: 4522782

Abstract

Bacteriophage T5 is known to contain several unique single-strand interruptions in only one strand of the duplex DNA. Analysis of labeled parental phage DNA from infected Escherichia coli shows that these nicks are repaired in vivo to yield intact double-stranded molecules. Sealing begins at about 6 min after infection and is independent of DNA replication. Repair may be an ordered process that starts at a unique end of the molecule.

Keywords: DNA replication, colIb, gel electrophoresis

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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