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. 1974 Mar;71(3):962–965. doi: 10.1073/pnas.71.3.962

Human Antigen and Enzyme Markers in Man-Chinese Hamster Somatic Cell Hybrids: Evidence for Synteny Between the HL-A, PGM3, ME1, and IPO-B Loci

H Van Someren †,‡,*, A Westerveld , A Hagemeijer §, J R Mees , P Meera Khan , O B Zaalberg
PMCID: PMC388137  PMID: 4362641

Abstract

In man-Chinese hamster somatic cell hybrids the segregation of the loci for 27 human enzyme markers and the species-specific surface antigens, including the HL-A histocompatibility antigens, was studied. The results show a synteny of the human loci for phosphoglucomutase 3, cytoplasmic malic enzyme, tetrameric indophenol oxidase, and HL-A. Furthermore, evidence is presented that the loci for the human species-specific antigens are distributed over several chromosomes.

Keywords: human gene linkage, species-specific antigens

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Selected References

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