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. Author manuscript; available in PMC: 2014 Sep 12.
Published in final edited form as: Neonatology. 2013 Sep 12;104(3):10.1159/000353721. doi: 10.1159/000353721

Figure 2. Global Analysis of altered Pathways and Networks in the NEC samples.

Figure 2

Several pathways were identified based on the altered proteome; these pathways are believed to be central to the pathogenesis of NEC. These processes include inflammation, cell death, oxidative stress, cell migration and apoptosis. The red color shows up-regulated proteins prior to NEC onset. The green color shows proteins that are down-regulated. The shape of a given protein is indicative of its functional class as shown in the legend. Also included in the legend is the definition of the lines connecting 2 proteins.