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. 1974 May;71(5):1677–1680. doi: 10.1073/pnas.71.5.1677

The Effect of Erythropoietin on Colonial Growth of Erythroid Precursor Cells In Vitro

Marvin C Cooper 1,2,*, Joseph Levy 1,2, Linda N Cantor 1,2, Paul A Marks 1,2, Richard A Rifkind 1,2,†
PMCID: PMC388301  PMID: 4525458

Abstract

A method is described for the colonial growth, in semi-solid medium, of erythropoietin-responsive erythroid cell precursors. The erythroid cell precursors were isolated by immune hemolysis from fetal mouse liver. Both the number of precursor cells triggered to proliferate and differentiate, and the size of the erythropoietic colonies formed, are directly dependent upon the concentration of erythropoietin included in the culture.

Keywords: fetal-mouse liver, cell culture, hemoglobin synthesis, differentiation, hormone

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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