Skip to main content
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1974 May;71(5):1816–1818. doi: 10.1073/pnas.71.5.1816

Gene Duplication and Fixed Heterozygosity for Alcohol Dehydrogenase in the Diploid Plant Clarkia franciscana

L D Gottlieb 1
PMCID: PMC388332  PMID: 4525465

Abstract

All individuals of the diploid plant Clarkia franciscana, an annual species native to California, have duplicated genes for the dimeric enzyme alcohol dehydrogenase. Since each gene specifies a polypeptide with a distinct charge, the species has a fixed heterozygous phenotype consisting of three isozyme variants. The enzyme is coded by a single gene in closely related species. Clarkia franciscana is highly self-pollinated and monomorphic at all but one of its loci that have been examined. Consequently, the duplication provides enzyme variability in the absence of genetic variability.

Keywords: plant evolution, isozyme polymorphisms, electrophoresis

Full text

PDF
1816

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Fincham J. R. Heterozygous advantage as a likely general basis for enzyme polymorphisms. Heredity (Edinb) 1972 Jun;28(3):387–391. doi: 10.1038/hdy.1972.49. [DOI] [PubMed] [Google Scholar]
  2. Schwartz D., Endo T. Alcohol Dehydrogenase Polymorphism in Maize-simple and Compound Loci. Genetics. 1966 Apr;53(4):709–715. doi: 10.1093/genetics/53.4.709. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES