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. Author manuscript; available in PMC: 2014 Aug 27.
Published in final edited form as: Oncogene. 2013 Mar 11;33(9):1181–1189. doi: 10.1038/onc.2013.42

Figure 1.

Figure 1

Expression level of miR-486-5p is lower in lung tumor tissues than in the matched normal lung tissues and the reduced expression is associated with advanced clinical stage and lymph node metastasis of NSCLC. (a) miR-486-5p expression level was considerably lower in NSCLC tissues than in their matched normal tissues. The expression level of miR-486-5p was assessed in 76 pairs of primary NSCLC frozen tissues and the corresponding normal lung tissues using qRT–PCR. U6 small nuclear RNA was used as an internal control. (b) Low-level expression of miR-486-5p was associated with high tumor stage of NSCLC (P<0.001). (c) Low-level expression of miR-486-5p was related with lymph node metastasis of NSCLC (P =0.0019).