TABLE 1.
Species | Prion strain | PrPC substrate (mouse line) | Limiting dilution of brain material |
---|---|---|---|
Mouse | 139A | Mouse (tga20) | 10−8 |
RML | 10−9 | ||
Chandler | 10−7 | ||
22L | 10−9 | ||
BSE | 10−10 | ||
ME7 | 10−6 | ||
Hamster | Sc237 | Hamster (tg7) | 10−7 |
263K | 10−7 | ||
HY | 10−7 | ||
DY | 10−5 | ||
Human | vCJD | Human M129 (tg650) | 10−8 |