SEM analysis of TMJ shape-specific neotissue at t = 5 wk, with images of control, BM, BA, and BM+BA for both band and middle zone regions. To measure collagen fibril diameter and density, three locations on three fibrocartilage constructs from each treatment were quantified. Results found BM+BA to promote synergistically thicker and significantly denser collagen fibrilsin both construct regions over all treatments. Both BA and BM+BA constructs presented with bundling of fibers aligning predominantly in the AP direction of their respective middle zones. Bars not connected by the same letter are significantly different (p < 0.05). Scale bar is 2 μm. ML = mediolateral, AP = anteroposterior.