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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1974 Aug;71(8):2992–2995. doi: 10.1073/pnas.71.8.2992

Long Pyrimidine Tracts of L-Cell DNA: Localization to Repeated DNA

N A Straus *, H C Birnboim
PMCID: PMC388605  PMID: 4528633

Abstract

Like HeLa DNA, L-cell DNA contains a significant number of unexpectedly long pyrimidine tracts. 1.3% of the thymidine residues of L-cell DNA are found in these long polypyrimidine tracts. Analysis of L-cell DNA fractions with different rates of reassociation indicates that polypyrimidine tracts are associated with “repeated” DNA. Longer pyrimidine tracts appear to have a higher repetition frequency than shorter tracts, and some may be repeated as many as 5 × 104 times in L-cell DNA.

Keywords: polypyrimidines, DNA reassociation, reiterated DNA

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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