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. 1974 Aug;71(8):3129–3133. doi: 10.1073/pnas.71.8.3129

Translation In Vitro of Total Nuclear RNA from HeLa Cell Nuclei Infected with Adenovirus 2

Nando K Chatterjee 1, Herbert Weissbach 1
PMCID: PMC388635  PMID: 4370520

Abstract

Total heterogeneous nuclear RNA from HeLa cells infected with adenovirus for 18-20 hr stimulates amino acid incorporation into protein in a cell-free system from Ehrlich ascites tumors. This stimulation of protein synthesis by the nuclear RNA requires intact nuclei. The role of nuclei in this system is unknown, but evidence is presented that the nuclei are involved in the conversion of high-molecular-weight RNA to low-molecular-weight species. Some of the newly synthesized polypeptides appear to resemble the virion polypeptides.

Keywords: nucleus, protein synthesis, DNA virus

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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