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. 1974 Aug;71(8):3208–3211. doi: 10.1073/pnas.71.8.3208

Differentiation of Cell Membranes in Cultures of Embryonic Chick Breast Muscle

Joav M Prives *, Bruce M Paterson †
PMCID: PMC388652  PMID: 4528510

Abstract

Three components of differentiated muscle membrane, the acetylcholine receptor, acetylcholinesterase (EC 3.1.1.7; acetylcholine hydrolase), and adenylate cyclase [EC 4.6.1.1; ATP pyrophosphate-lyase (cyclizing)], appear simultaneously during myogenesis in cultures of embryonic chick muscle, after the main period of rapid cell fusion. However, unlike the cytoplasmic proteins of differentiated muscle, the elaboration of these membrane components is unaltered when fusion is blocked by lowering the calcium concentration in the medium. These results suggest that membrane differentiation and cytoplasmic differentiation are regulated independently during muscle development.

Keywords: acetylcholine receptor, acetylcholinesterase, adenylate cyclase, cell fusion

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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