Abstract
Spider-like forms of purified reovirus RNA have been characterized by electron microscopy. These structures contained 11.3 +/- 0.8 mum of double-stranded RNA and up to 20 arms, each of distinct length. Length measurements of 64 "spiders" suggest that in these structures the viral genome is folded fairly specifically.
Full text
PDF




Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brown D. T., Westphal M., Burlingham B. T., Winterhoff U., Doerfler W. Structure and composition of the adenovirus type 2 core. J Virol. 1975 Aug;16(2):366–387. doi: 10.1128/jvi.16.2.366-387.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dunnebacke T. H., Kleinschmidt A. K. Ribonucleic acid from reovirus as seen in protein monolayers by electron microscopy. Z Naturforsch B. 1967 Feb;22(2):159–164. doi: 10.1515/znb-1967-0210. [DOI] [PubMed] [Google Scholar]
- Farrell J. A., Harvey J. D., Bellamy A. R. Biophysical studies of reovirus type 3. Virology. 1974 Nov;62(1):145–153. doi: 10.1016/0042-6822(74)90310-9. [DOI] [PubMed] [Google Scholar]
- LUDLUM D. B., WARNER R. C. EQUILIBRIUM CENTRIFUGATION IN CESIUM SULFATE SOLUTIONS. J Biol Chem. 1965 Jul;240:2961–2965. [PubMed] [Google Scholar]
- Nonoyama M., Graham A. F. Appearance of defective virions in clones of reovirus. J Virol. 1970 Nov;6(5):693–694. doi: 10.1128/jvi.6.5.693-694.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shatkin A. J. Inactivity of purified reovirus RNA as a template for E. coli polymerases in vitro. Proc Natl Acad Sci U S A. 1965 Dec;54(6):1721–1728. doi: 10.1073/pnas.54.6.1721. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith R. E., Zweerink H. J., Joklik W. K. Polypeptide components of virions, top component and cores of reovirus type 3. Virology. 1969 Dec;39(4):791–810. doi: 10.1016/0042-6822(69)90017-8. [DOI] [PubMed] [Google Scholar]
- Spendlove R. S., McClain M. E., Lennette E. H. Enhancement of reovirus infectivity by extracellular removal or alteration of the virus capsid by proteolytic enzymes. J Gen Virol. 1970 Aug;8(2):83–94. doi: 10.1099/0022-1317-8-2-83. [DOI] [PubMed] [Google Scholar]
- Vasquez C., Kleinschmidt A. K. Electron microscopy of RNA strands released from individual Reovirus particles. J Mol Biol. 1968 May 28;34(1):137–147. doi: 10.1016/0022-2836(68)90240-4. [DOI] [PubMed] [Google Scholar]


