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. 1975 Nov;72(11):4592–4596. doi: 10.1073/pnas.72.11.4592

Oncornavirus-like particles released from arginine-deprived human lymphoblastoid cell lines.

M Kotler, H Balabanova, E Weinberg, A Friedmann, Y Becker
PMCID: PMC388769  PMID: 53842

Abstract

Type-C RNA tumor virus particles were released from three different human lymphoblastoid cell lines after incubation in arginine-deficient medium. The released virus-like particles were characterized by (a) their ability to band in sucrose gradients at a density of 1.16-1.18 g/ml; (b) the presence of an RNA-directed DNA polymerase activity resembling that of the oncornaviruses; and (c) isolation of cores that band at a density of 1.26-1.27 g/ml in sucrose gradients. Examination of the arginine-deprived human lymphoblastoid cell line strain P3HR-1 by electron microscopy revealed the presence of C-type particles in the intracellular spaces.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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