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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1975 Dec;72(12):5103–5106. doi: 10.1073/pnas.72.12.5103

Specific human B lymphocyte alloantigens linked to HL-A.

D L Mann, L Abelson, P Henkart, S D Harris, D B Amos
PMCID: PMC388884  PMID: 1082138

Abstract

Sera, previously found to react specifically with B lymphoid cultured cells, were tested on isolated T and B peripheral blood lymphocytes in a microcytotoxicity assay. Studies were performed on lymphocytes obtained from several large Amish families. The sera used in these studies were cytotoxic to peripheral blood, B lymphocytes, but not cytotoxic to T lymphocytes. The antigens detected followed the inheritance pattern of HL-A haplotypes. The strong linkage disequilibrium with HL-A antigens suggests that genes controlling the expression of B lymphocyte antigens are linked to genes controlling HL-A alloantigens.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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