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. 1971 Mar;68(3):600–604. doi: 10.1073/pnas.68.3.600

The Mechanism of Protein Synthesis Activation After Fertilization of Sea Urchin Eggs

S Metafora *, L Felicetti *, R Gambino *
PMCID: PMC388998  PMID: 5276769

Abstract

Upon fertilization of Paracentrotus lividus eggs, the ability of their ribosomes to form a ternary complex with poly(U) and phenylalanyl-tRNA is enhanced. In addition, it is possible to extract from ribosomes of the unfertilized egg a protein factor that inhibits polyphenylalanine synthesis by decreasing the binding of mRNA and aminoacyl-tRNA to the ribosomes. The observed increase in the rate of protein synthesis that occurs at fertilization could be accounted for by the removal of this inhibitory protein from the ribosomes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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