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. 1971 Apr;68(4):752–756. doi: 10.1073/pnas.68.4.752

RNA-Dependent RNA Polymerase Activity Associated with Virions and Subviral Particles of Myxoviruses

Nang-Ly Chow 1, Robert W Simpson 1
PMCID: PMC389035  PMID: 4325103

Abstract

In vitro RNA synthesis is catalyzed by an enzyme found in purified virions of each of nine influenza strains tested. The extent of [3H]UTP incorporation observed is strain dependent, with an obligate requirement for Mn2+ ions and RNA template. At least 30% of purified product RNA shows resistance to degradation by ribonuclease A and T1 before and after annealing with exogenous RNA from influenza virions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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