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. 1971 May;68(5):901–904. doi: 10.1073/pnas.68.5.901

Species-Specific and Interspecific Antigenic Determinants Associated with the Structural Protein of Feline C-Type Virus

S Oroszlan *, R J Huebner *, R V Gilden *
PMCID: PMC389076  PMID: 4102562

Abstract

The group-specific protein of feline leukemia viruses has been isolated by isoelectric focusing. This protein has a molecular weight, calculated from sodium dodecyl sulfate-acrylamide gel electrophoresis, of 25,000 and forms a resolved band in such gels when disrupted virions are analyzed. This protein contains both species-specific antigenic determinants, as well as interspecific cross-reactive determinants, as an integral part of its structure.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Duesberg P. H., Martin G. S., Vogt P. K. Glycoprotein components of avian and murine RNA tumor viruses. Virology. 1970 Aug;41(4):631–646. doi: 10.1016/0042-6822(70)90428-9. [DOI] [PubMed] [Google Scholar]
  2. Gardner M. B., Rongey R. W., Arnstein P., Estes J. D., Sarma P., Huebner R. J., Rickard C. G. Experimental transmission of feline fibrosarcoma to cats and dogs. Nature. 1970 May 30;226(5248):807–809. doi: 10.1038/226807a0. [DOI] [PubMed] [Google Scholar]
  3. Geering G., Aoki T., Old L. J. Shared viral antigen of mammalian leukaemia viruses. Nature. 1970 Apr 18;226(5242):265–266. doi: 10.1038/226265a0. [DOI] [PubMed] [Google Scholar]
  4. Geering G., Hardy W. D., Jr, Old L. J., de Harven E., Brodey R. S. Shared group-specific antigen of murine and feline leukemia viruses. Virology. 1968 Dec;36(4):678–680. doi: 10.1016/0042-6822(68)90199-2. [DOI] [PubMed] [Google Scholar]
  5. Gregoriades A., Old L. J. Isolation and some characteristics of a group-specific antigen of the murine leukemia viruses. Virology. 1969 Feb;37(2):189–202. doi: 10.1016/0042-6822(69)90198-6. [DOI] [PubMed] [Google Scholar]
  6. Hartley J. W., Rowe W. P., Capps W. I., Huebner R. J. Isolation of naturally occurring viruses of the murine leukemia virus group in tissue culture. J Virol. 1969 Feb;3(2):126–132. doi: 10.1128/jvi.3.2.126-132.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Oroszlan S., Fisher C. L., Stanley T. B., Gilden R. V. Proteins of the murine C-type RNA tumour viruses: isolation of a group-specific antigen by isoelectric focusing. J Gen Virol. 1970 Jul;8(1):1–10. doi: 10.1099/0022-1317-8-1-1. [DOI] [PubMed] [Google Scholar]
  8. Oroszlan S., Foreman C., Kelloff G., Gilden R. V. The group-specific antigen and other structural proteins of hamster and mouse C-type viruses. Virology. 1971 Mar;43(3):665–674. doi: 10.1016/0042-6822(71)90290-x. [DOI] [PubMed] [Google Scholar]
  9. Schäfer W., Anderer F. A., Bauer H., Pister L. Studies on mouse leukemia viruses. I. Isolation and characterization of a group-specific antigen. Virology. 1969 Jul;38(3):387–394. doi: 10.1016/0042-6822(69)90151-2. [DOI] [PubMed] [Google Scholar]
  10. Schäfer W., Lange J., Pister L., Seifert E., De Noronha F., Schmidt F. W. Vergleichende serologische Untersuchungen über Leukämieviren. Eine Komplementbindungsreaktion zum Nachweis der bei Leukämieviren verschiedener Säuger vorkommenden gemeinsamen antigenen Komponente. Z Naturforsch B. 1970 Sep;25(9):1029–1036. [PubMed] [Google Scholar]
  11. Theilen G. H., Kawakami T. G., Rush J. D., Munn R. J. Replication of cat leukemia virus in cell suspension cultures. Nature. 1969 May 10;222(5193):589–590. doi: 10.1038/222589b0. [DOI] [PubMed] [Google Scholar]

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