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. 1971 Jun;68(6):1117–1120. doi: 10.1073/pnas.68.6.1117

Evidence for the Existence of Several Molecular Species in the “45S Fraction” of Mammalian Ribosomal Precursor RNA

Pierre Tiollais 1, Francis Galibert 1, Michel Boiron 1
PMCID: PMC389132  PMID: 5288361

Abstract

Analysis of RNA (after 5 or 60 min of labeling with [3H]uridine) from L5178Y cells by electrophoresis in 1.7% polyacrylamide gels demonstrates that the ribosomal RNA “45S fraction“ is not homogeneous but consists of at least three molecular species, conventionally designated 47S RNA, 46S RNA, and 45S RNA. Alternatives to the classical scheme for the biosynthesis of ribosomal RNA in mammalian cells are discussed.

Keywords: gel electrophoresis, actinomycin D, L5178Y cells, HeLa cells

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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