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. 1971 Jun;68(6):1279–1282. doi: 10.1073/pnas.68.6.1279

Local Supply of Energy to the Fast Axoplasmic Transport Mechanism

Sidney Ochs 1
PMCID: PMC389171  PMID: 5288375

Abstract

Local anoxia of a small region of cat sciatic nerves causes a block of fast axoplasmic transport in vitro. Activity becomes dammed up at the face of the anoxic region, and falls off rapidly distally just inside the anoxic region. Such blocks were reversible if they were removed within 1 hr. Earlier studies had given evidence that fast axoplasmic transport is closely dependent on ATP derived from oxidative metabolism. The present results indicate that ATP is required all along the length of the nerve fiber to supply a hypothesized “transporting filament” mechanism of fast transport.

Keywords: cat, in vitro

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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