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. 1971 Jun;68(6):1336–1340. doi: 10.1073/pnas.68.6.1336

Polyadenylic Acid Sequences in the Heterogeneous Nuclear RNA and Rapidly-Labeled Polyribosomal RNA of HeLa Cells: Possible Evidence for a Precursor Relationship

Mary Edmonds 1, Maurice H Vaughan Jr 1, Hiroshi Nakazato 1
PMCID: PMC389184  PMID: 5288383

Abstract

Polyadenylate sequences have been found covalently linked in heterogeneous DNA-like nuclear RNA of HeLa cells. This poly(A) material seems homogeneous in size and accounts for about 0.5% of such RNA. Similar poly(A) sequences were found in rapidly-labeled polyribosomal RNA, thought to be messenger RNA. A possible model for mRNA synthesis from large heterogeneous nuclear RNA precursor molecules is discussed.

Keywords: messenger RNA, poly(dT)-cellulose

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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