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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1971 Aug;68(8):1665–1669. doi: 10.1073/pnas.68.8.1665

Specific Heterologous Enhancement of Immune Responses

Arnold S Rubin 1, Albert H Coons 1
PMCID: PMC389266  PMID: 4942910

Abstract

In suspension cultures of mouse spleen cells, the addition of small amounts (1-100 ng) of a heterologous antigen to which the donor mice had been primed significantly increased the number of anti-sheep erythrocyte plaques appearing after stimulation with sheep erythrocytes. A similar addition to identical cultures from unprimed donors produced a small depression in the number of such plaques.

Keywords: mouse spleen cells, sheep erythrocytes, tetanus toxoid

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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