Abstract
2′,5′ - dimethyl - N(4′)benzyl - N(4′) - [desmethyl]rifampicin, a derivative of rifampicin, is used to acquire autoradiographic evidence that RNA-dependent DNA synthesis is involved in gene amplification during the early oogenesis of Xenopus laevis.
Keywords: autoradiography; 2′,5′-dimethyl-N(4′)benzyl-N(4′)[desmethyl]; rifampicin
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Crippa M., Tocchini-Valentini G. P. Synthesis of amplified DNA that codes for ribosomal RNA. Proc Natl Acad Sci U S A. 1971 Nov;68(11):2769–2773. doi: 10.1073/pnas.68.11.2769. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dawid I. B., Brown D. D., Reeder R. H. Composition and structure of chromosomal and amplified ribosomal DNA's of Xenopus laevis. J Mol Biol. 1970 Jul 28;51(2):341–360. doi: 10.1016/0022-2836(70)90147-6. [DOI] [PubMed] [Google Scholar]
- Ficq A. RNA synthesis in early oogenesis of Xenopus laevis. Exp Cell Res. 1970 Dec;63(2):453–457. doi: 10.1016/0014-4827(70)90237-5. [DOI] [PubMed] [Google Scholar]
- Gall J. G., Pardue M. L. Formation and detection of RNA-DNA hybrid molecules in cytological preparations. Proc Natl Acad Sci U S A. 1969 Jun;63(2):378–383. doi: 10.1073/pnas.63.2.378. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gall J. G. The genes for ribosomal RNA during oögenesis. Genetics. 1969;61(1 Suppl):121–132. [PubMed] [Google Scholar]
- Gurgo C., Ray R. K., Thiry L., Green M. Inhibitors of the RNA and DNA dependent polymerase activities of RNA tumour viruses. Nat New Biol. 1971 Jan 27;229(4):111–114. doi: 10.1038/newbio229111a0. [DOI] [PubMed] [Google Scholar]
- Lancini G., Cricchio R., Thiry L. Antiviral activity of rifamycins and N-aminopiperazines. J Antibiot (Tokyo) 1971 Jan;24(1):64–66. doi: 10.7164/antibiotics.24.64. [DOI] [PubMed] [Google Scholar]
- Scolnick E. M., Aaronson S. A., Todaro G. J., Parks W. P. RNA dependent DNA polymerase activity in mammalian cells. Nature. 1971 Jan 29;229(5283):318–321. doi: 10.1038/229318a0. [DOI] [PubMed] [Google Scholar]
- Wallace H., Morray J., Langridge W. H. Alternative model for gene amplification. Nat New Biol. 1971 Apr 14;230(15):201–203. doi: 10.1038/newbio230201a0. [DOI] [PubMed] [Google Scholar]