Figure 4. Angiogenesis inhibition of the chick CAM induced by BDD073 (n = 8). The development of micro-vessels was induced by 20 µg GST-VEGF-D. Note that the number of micro vessels was reduced by the presence of BDD073 in a dose-dependent manner. It suggested that BDD073 have neutralizing activities in the chick CAM (*, P < 0.05). a. Control GST (20µg), b. GST-VEGF-D (20 µg), c. GST-VEGF-D (20 µg) + BDD073 (5 µg), d. GST-VEGF-D (20 µg) + BDD073 (10 µg).