Abstract
Satellite bacteriophage P4 induces a new transcribing enzyme that synthesizes polyriboguanylic acid in the presence of the poly(dG)·poly(dC) homopolymer pair. This transcribing activity was partially purified and shown to be distinct from the host RNA polymerase. Analysis of conditional lethal mutants suggests that this new enzyme is necessary for replication of phage DNA.
Keywords: helper-dependent, RNA polymerase, DNA synthesis
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