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. 1972 Oct;69(10):3014–3018. doi: 10.1073/pnas.69.10.3014

Recognition of Nonsense Codons in Mammalian Cells

Dolph Hatfield 1
PMCID: PMC389697  PMID: 4562751

Abstract

The tritiated trinucleotide UGA was used in a binding assay to detect transfer RNAs that recognize this nonsense codon from calf-liver cells. Acylation of transfer RNA with labeled amino acids and determination of codon responses of aminoacyl-tRNAs demonstrate that a species of seryl-tRNA and a species of arginyl-tRNA recognize the codon UGA. Slight responses of cysteinyl-tRNA and of trytophanyl-tRNA to the codon UGA were also observed.

Keywords: calf liver, aminoacyl-tRNA synthetases, codon UGA

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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