Abstract
An unusual Salmonella typhimurium hybrid with sensitivity to coliphage λ and salmonella phage P22 has been recovered from matings between an Escherichia coli K-12 Hfr donor and an S. typhimurium recipient. The hybrid is an excellent host for achieving genetic recombination between λ and P22. Two broad classes of hybrid phages were isolated. The λ-P22 hybrid class, which has the protein coat of λ, contains at least the c region of P22. The P22-λ hybrid class has the protein coat of P22 and has inherited at least the c marker of λ.
Keywords: intergeneric conjugation, bacterial viruses, recombination
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BARON L. S., SPILMAN W. M., CAREY W. F. Diploid heterozygous hybrids from matings between Escherichia coli and Salmonella typhosa. J Exp Med. 1960 Aug 1;112:361–372. doi: 10.1084/jem.112.2.361. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Baron L. S., Penido E., Ryman I. R., Falkow S. Behavior of coliphage lambda in hybrids between Escherichia coli and Salmonella. J Bacteriol. 1970 Apr;102(1):221–233. doi: 10.1128/jb.102.1.221-233.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Baron L. S., Ryman I. R., Johnson E. M., Gemski P., Jr Lytic replication of coliphage lambda in Salmonella typhosa hybrids. J Bacteriol. 1972 Jun;110(3):1022–1031. doi: 10.1128/jb.110.3.1022-1031.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Falkow S., Rownd R., Baron L. S. GENETIC HOMOLOGY BETWEEN ESCHERICHIA COLI K-12 AND SALMONELLA. J Bacteriol. 1962 Dec;84(6):1303–1312. doi: 10.1128/jb.84.6.1303-1312.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gemski P., Jr, Stocker B. A. Transduction by bacteriophage P22 in nonsmooth mutants of Salmonella typhimurium. J Bacteriol. 1967 May;93(5):1588–1597. doi: 10.1128/jb.93.5.1588-1597.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KAISER A. D. A genetic study of the temperate coliphage. Virology. 1955 Nov;1(4):424–443. doi: 10.1016/0042-6822(55)90036-2. [DOI] [PubMed] [Google Scholar]
- LEVINE M. Mutations in the temperate phage P22 and lysogeny in Salmonella. Virology. 1957 Feb;3(1):22–41. doi: 10.1016/0042-6822(57)90021-1. [DOI] [PubMed] [Google Scholar]
- Lieb M. Studies of heat-inducible lambda bacteriophage. I. Order of genetic sites and properties of mutant prophages. J Mol Biol. 1966 Mar;16(1):149–163. doi: 10.1016/s0022-2836(66)80269-3. [DOI] [PubMed] [Google Scholar]
- Morse M L, Lederberg E M, Lederberg J. Transductional Heterogenotes in Escherichia Coli. Genetics. 1956 Sep;41(5):758–779. doi: 10.1093/genetics/41.5.758. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sanderson K. E. Current linkage map of Salmonella typhimurium. Bacteriol Rev. 1970 Jun;34(2):176–193. doi: 10.1128/br.34.2.176-193.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Taylor A. L. Current linkage map of Escherichia coli. Bacteriol Rev. 1970 Jun;34(2):155–175. doi: 10.1128/br.34.2.155-175.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wilkinson R. G., Gemski P., Jr, Stocker B. A. Non-smooth mutants of Salmonella typhimurium: differentiation by phage sensitivity and genetic mapping. J Gen Microbiol. 1972 May;70(3):527–554. doi: 10.1099/00221287-70-3-527. [DOI] [PubMed] [Google Scholar]
- YAMAMOTO N., ANDERSON T. F. Genomic masking and recombination between serologically unrelated phages P22 and P221. Virology. 1961 Aug;14:430–439. doi: 10.1016/0042-6822(61)90334-8. [DOI] [PubMed] [Google Scholar]
- Yamamoto N. Genetic evolution of bacteriophage. I. Hybrids between unrelated bacteriophages P22 and Fels 2. Proc Natl Acad Sci U S A. 1969 Jan;62(1):63–69. doi: 10.1073/pnas.62.1.63. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yamamoto N. The origin of bacteriophage P221. Virology. 1967 Nov;33(3):545–547. doi: 10.1016/0042-6822(67)90132-8. [DOI] [PubMed] [Google Scholar]
- ZINDER N. D., LEDERBERG J. Genetic exchange in Salmonella. J Bacteriol. 1952 Nov;64(5):679–699. doi: 10.1128/jb.64.5.679-699.1952. [DOI] [PMC free article] [PubMed] [Google Scholar]
