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. 1972 Nov;69(11):3195–3198. doi: 10.1073/pnas.69.11.3195

Precursor and Product in Bacteriophage λ Recombination

Norman E Melechen 1, T A Hudnik-Plevnik 1,*
PMCID: PMC389734  PMID: 4564207

Abstract

Analyses of the time of recombination in bacteria infected with phage λ and in spheroplasts infected with purified phage λ DNA indicate a preponderance of recombination occurring before replication (“early recombination”) after infection with tandem dimers formed in vitro compared to linear monomer DNA and phage infections. Among the early recombinants is a large fraction of cells that produces one recombinant type exclusively. Two suggestions are discussed—that a dimer-like molecule is the precursor of the recombinant progeny molecule and that one recombinant chromosome is the frequent or exclusive product of a recombinational event.

Keywords: genetic recombination, recombination mechanism, phage dimers, dimer transfection

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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