Table 2. Vitamin D status affects atopic dermatitis presentation after 3 mo supplementation 2000 IU/day cholecalciferol (adapted from 25).
| Before | After | p-value | |||
|---|---|---|---|---|---|
| range | x ± SD | range | x ± SD | ||
| SCORAD index | 26 -78 | 45.12 ± 16.07 | 10 – 49 | 25.70 ± 11.10 | 0.001 |
| Extent % | 10 - 80 | 30.35 ± 23.48 | 10 - 20 | 19.90 ± 18.64 | 0.01 |
| Intensity | 4 -15 | 8.55 ± 2.85 | 2 - 9 | 4.05 ± 2.11 | 0.001 |
| Erythema | 0 -3 | 1.3 ± 0.73 | 0 - 2 | 0.5 ± 0.76 | 0.01 |
| Edema/papulation | 1 - 3 | 1.35 ± 0.58 | 0 - 1 | 0.15 ± 0.36 | 0.001 |
| Oozing/crust | 0 - 2 | 0.6 ± 0.68 | 0 | 0 | 0.01 |
| Excoriation | 0 - 3 | 0.85 ± 0.67 | 0 - 2 | 0.2 ± 0.52 | 0.01 |
| Lichenification | 1 - 3 | 2.05 ± 0.82 | 1 - 3 | 1.9 ± 0.78 | NS |
| Dryness | 1 - 3 | 2.4 ± 0.75 | 1 - 3 | 2.0 ± 0.72 | 0.05 |
| Subjective symptoms | 2 - 18 | 7.80 ± 3.96 | 0 - 13 | 4.20 ± 3.08 | 0.001 |
| Pruritus | 1 - 10 | 5.50 ± 2.52 | 1 - 7 | 2.85 ± 1.92 | 0.001 |
| Sleeplessness | 0 - 8 | 2.25 ± 2.29 | 0 - 6 | 1.45 ± 1.66 | 0.05 |
| Objective SCORAD | 18 – 68 | 37.09 ± 15.17 | 9 – 44 | 20.85 ± 9.94 | 0.001 |
| IgE level IU/ml | 6.6–7100 | 1147.56 ± 1883.85 | 6.3–6150 | 994.86 ± 1680.71 | 0.001 |
| Vitamin D level ng/ml | 4.0 – 15.0 | 7.43 ± 3.34 | 5.01 – 23.87 | 13.05 ± 5.49 | 0.001 |