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. 1972 Nov;69(11):3385–3388. doi: 10.1073/pnas.69.11.3385

Synthesis of Proteochondroitin Sulfate by Normal, Nanomelic, and 5-Bromodeoxyuridine-Treated Chondrocytes in Cell Culture

M J Palmoski 1, P F Goetinck 1
PMCID: PMC389776  PMID: 4508328

Abstract

Chondrocytes grown in cell culture from micromelic chick sterna and 5-bromodeoxyuridine-treated normal cells showed reduced incorporation of sulfate into hyaluronidase-sensitive material as compared to normal chondrocytes. Proteochondroitin sulfate synthesized by normal embryonic chick chondrocytes in cell culture was heterogeneous on chromatography. The major chromatographic component was specifically inhibited in normal chondrocytes treated with 5-bromodeoxyuridine, and this component was absent in nanomelic chondrocytes.

Keywords: hyaluronidase, chick embryos, chromatographic heterogeneity

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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