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SH2B1 is highly expressed in pancreatic β-cells. A: Pancreas sections from WT and KO mice were immunostained with anti-SH2B1 (red) and anti-insulin (green) antibodies. Scale bar: 250 μm. B: Pancreas and islets extracts were immunoprecipitated (IP) and immunoblotted (IB) with anti-SH2B1 antibody. Extracts were also blotted with anti–β-actin antibody.
