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. 2012 May 10;1(2):127–140. doi: 10.3390/cells1020127

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© 2012 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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During mixed lymphocyte reactions soluble factors are likely involved with proliferation. Associations between CD4 T cell and CD8 T cell (panel A), between CD4 T cell and CD4-/CD8- cell (panel B), and between CD8 T cellCD4 T cell and CD4-/CD8- cell (panel C) proliferation as determined by CFSE dye dilution method for reactions described in Figure 4.