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Diagnostic performance of ELISPOT-detected Borrelia-induced Interferon-γ secretion in patients with Lyme neuroborreliosis and non-Lyme neuroborreliosis, utilizing different cut-offs.
| Diagnostic groups | ELISPOT cut-off ≥5 spots | ELISPOT cut-off ≥10 spots | ||
|---|---|---|---|---|
| Positive | Negative | Positive | Negative | |
| Lyme neuroborreliosis (n = 14) | 5 (36%) | 9 (64%) | 3 (21%) | 11 (79%) |
| Non-Lyme borreliosis (n = 103) | 19 (18%) | 84 (82%) | 8 (8%) | 95 (92%) |
