Table 1.
Odds ratios with 95% confidence intervals for outcome variables according to pertussis vaccination status
| Outcome variable | Non-vaccinated* | Partially vaccinated† | Fully vaccinated‡ | P value |
|---|---|---|---|---|
|
Asthma at age 69-81 months (1024/8240)
|
|
|
|
|
| Prevalence in % (No/total) | 8.2 (12/146) | 20.3 (14/69) | 12.4 (998/8025) | |
| Unadjusted | 1.00 | 2.84 (1.24 to 6.53) | 2.05 (0.8 to 5.23) | 0.05 |
| Adjusted | 1.00 | 1.59 (0.88 to 2.97) | 1.06 (0.58 to 1.95) | >0.1 |
|
Periods of wheeze at age 69-81 months (798/8114)
|
|
|
||
| Prevalence in % (No/total) | 9.0 (13/144) | 16.2 (11/68) | 9.8 (774/7902) | |
| Unadjusted | 1.00 | 1.95 (0.82 to 4.6) | 1.09 (0.62 to 1.94) | 0.2 |
| Adjusted | 1.00 | 1.55 (0.55 to 4.37) | 0.94 (0.50 to 1.78) | 0.2 |
|
Doctor diagnosed asthma at age 91 months (1597/7850)
|
|
|
||
| Prevalence in % (No/total) | 15.8 (23/146) | 36.2 (21/58) | 20.3 (1553/7667) | |
| Unadjusted | 1.00 | 3.03 (1.51 to 6.09) | 1.36 (0.87 to 2.13) | 0.005 |
| Adjusted | 1.00 | 1.93 (0.86 to 4.33) | 0.98 (0.61 to 1.58) | 0.1 |
|
Atopy at age 7 years (1324/6463)
|
|
|
|
|
| Prevalence in % (No) | 17.7 (22/124) | 15.4 (6/39) | 20.6 (1296/6300) | |
| Unadjusted | 1.00 | 0.84 (0.32 to 2.26) | 1.20 (0.75 to 1.91) | 0.6 |
| Adjusted | 1.00 | 1.05 (0.35 to 3.21) | 1.18 (0.69 to 2.03) | 0.8 |
*
No primary vaccinations, including pertussis.
†
Diphtheria and tetanus ≥3 doses and no pertussis.
‡
Triple (diphtheria, tetanus, and pertussis) vaccine ≥3 doses.