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. Author manuscript; available in PMC: 2014 Dec 23.
Published in final edited form as: Biochemistry. 2013 Nov 26;52(51):9286–9293. doi: 10.1021/bi4013319

Figure 5.

Figure 5

“The Change in Isotopic Composition Over Time by Mass Spectrometry.” A) Conversion of isocitrate to mono-deuterated isocitrate. B) Conversion of succinate to di-deuterated succinate through a transient mono-deuterated succinate species.