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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1996 Jun 25;93(13):6671–6675. doi: 10.1073/pnas.93.13.6671

A distribution of tumor size at detection and its limiting form.

A Y Yakovlev 1, L G Hanin 1, S T Rachev 1, A D Tsodikov 1
PMCID: PMC39084  PMID: 8692876

Abstract

A distribution of tumor size at detection is derived within the framework of a mechanistic model of carcinogenesis with the object of estimating biologically meaningful parameters of tumor latency. Its limiting form appears to be a generalization of the distribution that arises in the length-biased sampling from stationary point processes. The model renders the associated estimation problems tractable. The usefulness of the proposed approach is illustrated with an application to clinical data on premenopausal breast cancer.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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