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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Prostate. 2013 Aug 26;73(16):1824–1835. doi: 10.1002/pros.22721

TABLE II.

Association of Genetic Score and Prostate Biopsy Outcomes

29 SNPs 24 SNPs
Genetic score (median)
  PCa 1.09 1.19
  Non-PCa 0.88 0.88
  P-Value 6.05 × 10−6 5.61 × 10−7
Association with PCa, OR (95% CI)
  Genetic score ≤1.0 1 1
  Genetic score >1.0 1.76 (1.39–0.23) 1.92 (1.49–0.45)
  P-Value 2.75 × 10−6 3.20 × 10−7
Discrimination of PCa
  AUC (95% CI) 0.60 0.61
Detection rate of PCa (%)
  Genetic score <0.5 29.52 30.95
  Genetic score =0.5–1.49 36.10 34.96
  Genetic score ≥1.5 50.85 52.30
  P-Value 0.0001 9.14 × 10−5